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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • GHSR Antibodies

          Invitrogen

          GHSR Monoclonal Antibody (502430)

          查看其他9个GHSR抗体

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          Cite GHSR Monoclonal Antibody (502430)

          • 抗体检测数据 (1)
          GHSR Antibody in Flow Cytometry (Flow)
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          GHSR Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.

          图: 1 / 1

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          GHSR Antibody (MA5-61943) in Flow

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          GHSR Antibody in Flow Cytometry (Flow)

          产品信息

          MA5-61943

          应用
          建议稀释比
          已发表文章

          流式细胞分析 (Flow)

          0.25 µg/10^6 cells
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Mouse / IgG1

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          502430

          抗原

          NS0 mouse myeloma cell line transfected with human GHSR

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Lyophilized

          浓度

          0.5 mg/mL

          纯化类型

          Protein A/G

          保存液

          PBS with trehalose

          内含物

          no preservative

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3702792

          产品详细信息

          Reconstitute at 0.5 mg/mL in sterile PBS.

          靶标信息

          Growth hormone secretagogue receptor 1a (GHSR) is a member of the G-protein coupled receptor family. GHSR may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations to the gene can cause isolated partial growth hormone deficiency.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: GH-releasing peptide receptor; Ghrelin receptor; GHRP; Ghrp receptor; GHS receptor; GHS-R; Growth hormone secretagogue receptor type 1

          查看更多 收起

          基因别名: GHDP; GHSR

          查看更多 收起

          UniProt ID: (Human) Q92847

          查看更多 收起

          Entrez Gene ID: (Human) 2693

          查看更多 收起

          功能
          growth hormone secretagogue receptor activity G-protein coupled receptor activity growth hormone-releasing hormone receptor activity peptide hormone binding G-protein coupled receptor
          参与通路
          G-protein coupled receptor signaling pathway actin polymerization or depolymerization adult feeding behavior response to hormone hormone-mediated signaling pathway growth hormone secretion response to food positive regulation of appetite negative regulation of interleukin-1 beta production cellular response to insulin stimulus positive regulation of multicellular organism growth negative regulation of tumor necrosis factor biosynthetic process regulation of hindgut contraction positive regulation of insulin-like growth factor receptor signaling pathway negative regulation of interleukin-6 biosynthetic process positive regulation of fatty acid metabolic process negative regulation of insulin secretion decidualization negative regulation of inflammatory response regulation of synapse assembly
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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