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Invitrogen
GIP Polyclonal Antibody
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GIP Antibody (PA5-50225) in IHC (P)
Immunohistochemistry analysis of GIP on paraffin-embedded rat kidney tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with GIP Polyclonal Antibody (Product # PA5-50225) at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained ... View More
产品信息
PA5-50225
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Fusion protein corresponding to a region derived from internal residues of human gastric inhibitory polypeptide
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 0.87% NaCl, 40% glycerol
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total GIP protein.
靶标信息
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Gastric inhibitory polypeptide; GIP; Glucose-dependent insulinotropic peptide; Glucose-dependent insulinotropic polypeptide; Incretin hormone; Rabbit Anti GIP
基因别名: GIP; Gludins; RATGLUDINS
UniProt ID: (Human) P09681, (Mouse) P48756, (Rat) Q06145
Entrez Gene ID: (Human) 2695, (Mouse) 14607, (Rat) 25040
signal transduction
female pregnancy
memory
adult locomotory behavior
response to glucose
response to selenium ion
response to acidic pH
positive regulation of glucose transport
response to organic cyclic compound
sensory perception of pain
endocrine pancreas development
positive regulation of insulin secretion
response to lipid
exploration behavior
response to drug
response to starvation
response to amino acid
response to peptide hormone
positive regulation of cAMP-mediated signaling
response to axon injury
regulation of insulin secretion
digestive system development
long-term synaptic potentiation
positive regulation of glucagon secretion
triglyceride homeostasis
positive regulation of synaptic transmission
response to carbohydrate
response to nutrient levels
