Search
Agrisera
GLDP/Glycine decarboxylase P protein Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 1
GLDP/Glycine decarboxylase P protein Antibody (AS20-4370) in WB
6 µg of total protein extracted freshly from Z. mays = Zea mays, A. tha= Arabidopsis thaliana, O. sat = Oryza sativa, was freshly extracted from leaf tissue in extraction buffer (50 m M HEPES-KOH p H 7.1,1 m M EDTA p H 8.0,10 m M DTT, 5 m M Mg Cl 2,1 m M PMSF, 20 µg/mL chymostatin, 25 µg/mL aprotinin, 1 X Protease Inhibitor Cocktail VI, Plant Cell (AG Scientific). Proteins were denatured with sample buffer ... View More
产品信息
AS20-4370
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated peptide, highly conserved in Arabidopsis thaliana GLDP1 and GLDP2.
偶联物
形式
Lyophilized
保存液
whole serum
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana, Flaveria spp., Neurachne spp.,Oryza sativa, Zea mays
靶标信息
GLDP encodes the mitochondrial P-protein of the glycine cleavage system, a soluble matrix enzyme that is imported via an N-terminal mitochondrial targeting sequence and functions as a pyridoxal 5-prime-phosphate (PLP)-dependent aminotransferase-like decarboxylase. The mature protein is a large PLP-binding enzyme with conserved catalytic motifs typical of class I/II aminotransferase fold enzymes and forms a functional homodimer, creating an active-site architecture that binds glycine and coordinates PLP to support catalysis; structural work on P-proteins supports a dimeric organization and highlights conserved residues near the active site that regulate access to the PLP/glycine-binding pocket. Biologically, the P-protein catalyzes the initial step of glycine degradation in one-carbon metabolism by decarboxylating glycine and transferring the resulting aminomethyl moiety to the lipoyl domain of the H-protein, thereby coupling glycine catabolism to folate-dependent one-carbon units and cellular redox/energy metabolism; loss of P-protein activity disrupts glycine clearance and impairs flux through mitochondrial one-carbon pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: AtGLDP1; F4I10.7; GLDP1; glycine decarboxylase P-protein 1
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
