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Invitrogen
GLI1 Monoclonal Antibody (CL12193)
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图: 1 / 6
GLI1 Antibody (MA573598) in ICC/IF
Immunocytochemistry analysis of GLI1 using RH-30 cells (showing specific staining in the nucleoplasm and cytosol in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available) ). Samples were incubated with GLI1 monoclonal antibody (Product # MA573598).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA573598
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
CL12193
抗原
Synthetic Peptide.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.989999999999999 mg/mL
规格
99 µg
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Highest antigen sequence identity to the following orthologs: Mouse- 95%, Rat- 95%.
靶标信息
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glioma-associated oncogene; Glioma-associated oncogene homolog; Oncogene GLI; zinc finger protein 5; Zinc finger protein GLI1
基因别名: AV235269; GLI; GLI1; Zfp-5; Zfp5
UniProt ID: (Mouse) P47806
Entrez Gene ID: (Mouse) 14632
osteoblast differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
signal transduction
smoothened signaling pathway
multicellular organism development
spermatogenesis
ventral midline development
positive regulation of cell proliferation
epidermal cell differentiation
dorsal/ventral pattern formation
proximal/distal pattern formation
cerebellar cortex morphogenesis
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
pituitary gland development
cell differentiation
lung development
positive regulation of DNA replication
positive regulation of smoothened signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
notochord regression
negative regulation of canonical Wnt signaling pathway
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
