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This target displays homology in the following species: Cow: 86%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 100%; Sheep: 86%
Glucagon-like peptide-1(9-36)amide and GLP-1(9-37) are the forms of GLP-1 that result from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GLP-1 receptor; GLP-1-R; GLP-I receptor; Glucagon-like peptide 1 receptor
基因别名: GLP-1R; Glp1r; GLP1Rc
UniProt ID: (Mouse) O35659
Entrez Gene ID: (Mouse) 14652
分子生物学功能: transmembrane signal receptor