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Invitrogen
GLUT4 Recombinant Rabbit Monoclonal Antibody (PSH10-06)
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GLUT4 Antibody (MA570111) in IHC (F)
Immunohistochemistry analysis of GLUT4 in frozen rat skeletal muscle tissue. Samples were incubated with GLUT4 monoclonal antibody (Product # MA570111) using a dilution of 1:500 overnight at 4°C, washed with PBS followed by Goat Anti-Rabbit IgG H&L (iFluor™ 488) at a dilution of 1:1,000. The section did not undergo antigen retrieval. The tissues were blocked in 10% negative goat serum for 1 hour at room tem... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA570111
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH10-06
抗原
Synthetic peptide within human GLUT4 C-term.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: Mouse heart tissue, rat skeletal muscle tissue, Mouse skeletal muscle tissue lysate.
Subcellular location: Cell membrane, Endomembrane system, Cytoplasm, perinuclear region.
靶标信息
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glucose transporter 4 insuline-responsive; Glucose transporter 4, insuline-responsive; glucose transporter glut4; Glucose transporter type 4, insulin-responsive; GLUT-4; GT2; insulin responsive glucose transporter; MGC93607; solute carrier family 2 member 4; solute carrier family 2 , member 4; Solute carrier family 2, facilitated glucose transporter member 4
基因别名: Glut-4; Glut4; Slc2a4
UniProt ID: (Rat) P19357, (Mouse) P14142
Entrez Gene ID: (Rat) 25139, (Mouse) 20528
amylopectin biosynthetic process
glucose transport
cellular response to insulin stimulus
hexose transmembrane transport
glucose homeostasis
response to ethanol
brown fat cell differentiation
transmembrane transport
cellular response to hypoxia
cellular response to osmotic stress
transport
carbohydrate transport
proton transport
glucose import
cation transmembrane transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
