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Invitrogen
GLUT4 Recombinant Rabbit Monoclonal Antibody (PSH10-06)
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GLUT4 Antibody (MA571371) in IHC (P)
Immunohistochemical analysis of was performed using formalin-fixed paraffin-embedded mouse skeletal muscle tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110°C for 15 min. Following antigen... View More
产品信息
MA571371
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH10-06
抗原
Synthetic peptide within human GLUT4 aa 447-509.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4, with 40% glycerol, 0.1% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control: Mouse heart tissue, rat skeletal muscle tissue, Mouse heart tissue lysate, Mouse skeletal muscle tissue lysate, Rat skeletal muscle tissue lysate.
Tissue Specificity: Tissue enhanced (heart muscle, skeletal muscle)
Subcellular Location: Cell membrane, Endomembrane system, Cytoplasm, perinuclear region.
Sequence Similarities: 96% Mouse/Rat
Predicted band size: 55 kDa.
靶标信息
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glucose transporter 4 insuline-responsive; Glucose transporter 4, insuline-responsive; glucose transporter glut4; Glucose transporter type 4, insulin-responsive; GLUT-4; GT2; insulin responsive glucose transporter; insulin-responsive glucose transporter; insulin-responsive glucose transporter type 4; MGC93607; solute carrier family 2 member 4; solute carrier family 2 (facilitated glucose transporter), member 4; solute carrier family 2 , member 4; Solute carrier family 2, facilitated glucose transporter member 4; unnamed protein product
基因别名: Glut-4; GLUT4; SLC2A4
UniProt ID: (Human) P14672, (Rat) P19357, (Mouse) P14142
Entrez Gene ID: (Human) 6517, (Rat) 25139, (Mouse) 20528
amylopectin biosynthetic process
glucose transport
cellular response to insulin stimulus
hexose transmembrane transport
glucose homeostasis
response to ethanol
brown fat cell differentiation
transmembrane transport
cellular response to hypoxia
cellular response to osmotic stress
carbohydrate metabolic process
learning or memory
short-term memory
long-term memory
positive regulation of brain-derived neurotrophic factor receptor signaling pathway
glucose import in response to insulin stimulus
glucose import
white fat cell proliferation
dehydroascorbic acid transport
cellular response to tumor necrosis factor
regulation of synaptic vesicle budding from presynaptic endocytic zone membrane
transport across blood-brain barrier
glucose transmembrane transport
transport
carbohydrate transport
proton transport
cation transmembrane transport
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