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Abnova
GLYATL1 Polyclonal Antibody, MaxPab™
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产品信息
H00092292-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GLYATL1 (NP_542392, 1 a.a. approximately 333 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MFKLCSNKMV SQEGSEVELL VSPGARSEHG RYLQDPIVSI DLSEWLRIIE FLLQGLKVYG SVYHINHGNP FNMEVLVDSW PEYQMVIIRP QKQEMTDDMD SYTNVYRMFS KEPQKSEEVL KNCEIVNWKQ RLQIQGLQES LGEGIRVATF SKSVKVEHSR ALLLVTEDIL KLNASSKSKL GSWAETGHPD DEFESETPNF KYAQLDVSYS GLVNDNWKRG KNERSLHYIK RCIEDLPAAC MLGPEGVPVS WVTMDPSCEV GMAYSMEKYR RTGNMARVMV RYMKYLRQKN IPFYISVLEE NEDSRRFVGQ FGFFEASCEW HQWTCYPQNL VPF
靶标信息
The GLYATL1 gene, also known as Glycine-N-Acyltransferase Like 1, is located on chromosome 11q12.1. This gene encodes a member of the glycine-N-acyltransferase family, which is involved in the detoxification pathway by catalyzing the conjugation of acyl-CoA substrates with glycine. The protein encoded by GLYATL1 is localized to the endoplasmic reticulum and is implicated in various cellular processes, including xenobiotic metabolism and mitochondrial glutamine metabolism. Studies have shown that the expression levels of GLYATL1 are significantly associated with cancer prognosis. For example, decreased expression of GLYATL1 has been linked to poor prognosis in patients with clear cell renal cell carcinoma (ccRCC). Furthermore, differential expression analysis has identified GLYATL1 as a potential biomarker in prostate cancer, suggesting its utility in cancer diagnostics and treatment strategies. The gene comprises multiple exons and undergoes alternative splicing, resulting in various transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acyl-CoA:glycine N-acyltransferase-like protein 1; Glutamine N-acyltransferase; Glycine N-acyltransferase-like protein 1; glycine-N-acyltransferase-like 1
基因别名: GATF-C; GLYATL1; GNAT
UniProt ID: (Human) Q969I3
Entrez Gene ID: (Human) 92292
