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Invitrogen
GLYATL1 Polyclonal Antibody
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产品信息
PA5-58816
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human GLYATL1. Recombinant protein control fragment (Product #RP-97458).
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: QGLQESLGEG IRVATFSKSV KVEHSRALLL VTEDILKLNA SSKSKLGSWA ETGHPDDEFE SETPNFKYAQ
Highest antigen sequence identity to the following orthologs: Mouse - 27%, Rat - 28%.
靶标信息
The GLYATL1 gene, also known as Glycine-N-Acyltransferase Like 1, is located on chromosome 11q12.1. This gene encodes a member of the glycine-N-acyltransferase family, which is involved in the detoxification pathway by catalyzing the conjugation of acyl-CoA substrates with glycine. The protein encoded by GLYATL1 is localized to the endoplasmic reticulum and is implicated in various cellular processes, including xenobiotic metabolism and mitochondrial glutamine metabolism. Studies have shown that the expression levels of GLYATL1 are significantly associated with cancer prognosis. For example, decreased expression of GLYATL1 has been linked to poor prognosis in patients with clear cell renal cell carcinoma (ccRCC). Furthermore, differential expression analysis has identified GLYATL1 as a potential biomarker in prostate cancer, suggesting its utility in cancer diagnostics and treatment strategies. The gene comprises multiple exons and undergoes alternative splicing, resulting in various transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acyl-CoA:glycine N-acyltransferase-like protein 1; Glutamine N-acyltransferase; Glycine N-acyltransferase-like protein 1; glycine-N-acyltransferase-like 1
基因别名: GATF-C; GLYATL1; GNAT
UniProt ID: (Human) Q969I3
Entrez Gene ID: (Human) 92292
