Search
Invitrogen
GNAI1/GNAI2/GNAI3 Recombinant Rabbit Monoclonal Antibody (HL2093)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 4
GNAI1/GNAI2/GNAI3 Antibody (MA5-50379) in WB
Western Blot analysis of GNAI1/GNAI2/GNAI3 using GNAI1/GNAI2/GNAI3 Recombinant Monoclonal Antibody (Product # MA5-50379) in A431 (30 μg) and HeLa (30 μg) whole cell extracts at a dilution of 1:1,000. Extracts were separated by 10% SDS-PAGE. An HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
产品信息
MA5-50379
产品规格
种属反应
Human,
Mouse,
Rat,
Zebrafish
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL2093
抗原
Recombinant fragment of human GNAI3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
GNAI1/GNAI2/GNAI3 are genes that encode for the G protein alpha inhibiting activity subunit. These proteins play a crucial role in signal transduction pathways, particularly in the inhibition of adenylyl cyclase. They are involved in various physiological processes, including neurotransmitter release, hormone secretion, and regulation of smooth muscle contraction. Mutations in these genes have been associated with various diseases, including hypoparathyroidism, pituitary adenoma, and cardiovascular disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Adenylate cyclase-inhibiting G alpha protein; G alpha inhibitory type 2 (a); G alpha inhibitory type 2 (b); G protein; G protein alpha subunit; G(i) alpha-3; Galpha i1a; Galpha i3; Gi1 protein alpha subunit; GNAI2; GTP-binding protein (G-alpha-i2); GTP-binding protein alpha subunit; GTP-binding regulatory protein Gi alpha-2 chain; guanine nucleotide binding protein (G protein), alpha inhibiting 1; guanine nucleotide binding protein (G protein), alpha inhibiting 2; guanine nucleotide binding protein (G protein), alpha inhibiting 3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3; guanine nucleotide binding protein, alpha inhibiting 1; guanine nucleotide binding protein, alpha inhibiting 2; guanine nucleotide binding protein, alpha inhibiting 3; Guanine nucleotide binding, protein, alpha inhibiting polypeptide 3; guanine nucleotide-binding protein (G) alpha subunit; guanine nucleotide-binding protein alpha-i subunit; guanine nucleotide-binding protein G(i) subunit alpha; Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding protein G(i) subunit alpha-3; guanine nucleotide-binding protein G(i), alpha-1 subunit; guanine nucleotide-binding protein G(i), alpha-2 subunit; guanine nucleotide-binding protein G(k) subunit alpha; guanine nucleotide-binding regulatory protein alpha-inhibitory subunit; heterotrimeric guanine nucleotide-binding protein 1A; heterotrimeric guanine nucleotide-binding protein 1B; heterotrimeric guanine nucleotide-binding protein 1C; HG1B/HG1C/HG1A; sGi2; unnamed protein product
基因别名: 87U6; AI158965; ARCND1; ARCODS; AU046200; AW537698; BPGTPB; C76432; Galphai2; Galphai3; Gi; Gia; Gialpha1; GIP; GIP3A; Gnai-1; Gnai-2; Gnai-3; GNAI1; GNAI2; GNAI2B; GNAI3; H_LUCA15.1; H_LUCA16.1; HG1A; HG1B; HG1C; NEDHISB; zgc:63957
nucleotide binding
magnesium ion binding
G-protein coupled receptor binding
GTPase activity
obsolete small monomeric GTPase activity
protein binding
GTP binding
adenylate cyclase regulator activity
adenylate cyclase inhibitor activity
hydrolase activity
guanyl nucleotide binding
GDP binding
G-protein beta/gamma-subunit complex binding
D2 dopamine receptor binding
G-protein coupled serotonin receptor binding
metal ion binding
signal transducer activity
GTPase activating protein binding
protein domain specific binding
heterotrimeric G-protein
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway
neuropeptide signaling pathway
response to prostaglandin E
response to peptide hormone
positive regulation of cholesterol biosynthetic process
negative regulation of insulin secretion
cell division
regulation of mitotic spindle organization
chemokine-mediated signaling pathway
T cell migration
positive regulation of relaxation of smooth muscle
cellular response to forskolin
positive regulation of protein localization to cell cortex
adenosine receptor signaling pathway
negative regulation of adenylate cyclase activity
G-protein coupled acetylcholine receptor signaling pathway
gamma-aminobutyric acid signaling pathway
response to nutrient
cell proliferation
positive regulation of cell proliferation
positive regulation of cell migration
positive regulation of superoxide anion generation
positive regulation of urine volume
negative regulation of calcium ion-dependent exocytosis
modulation of synaptic transmission
negative regulation of synaptic transmission
regulation of calcium ion transport
positive regulation of ERK1 and ERK2 cascade
negative regulation of adrenergic receptor signaling pathway
positive regulation of vascular smooth muscle cell proliferation
positive regulation of neural precursor cell proliferation
negative regulation of apoptotic signaling pathway
positive regulation of macroautophagy
GTP metabolic process
metabolic process
cell cycle
activation of MAPKK activity
G-protein coupled glutamate receptor signaling pathway
regulation of heart contraction
intracellular signal transduction
vesicle fusion
negative regulation of secretion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
