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Invitrogen
GNB3/GNB4 Polyclonal Antibody
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GNB3/GNB4 Antibody (PA5-19401) in IHC (P)
Immunohistochemistry analysis of GNB3/GNB4 in human brain, cerebellum. Samples were incubated with GNB3/GNB4 polyclonal antibody (Product # PA5-19401) using a dilution of 3.75 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
产品信息
PA5-19401
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (SGHDNRVSCLGVT) corresponding to the internal amino acids of GNB3 (aa 308-321).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
靶标信息
Heterotrimeric guanine nucleotide-binding proteins in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein beta-4 subunit; G protein, beta-3 subunit; gbb3; gbb4; GTP-binding regulatory protein beta-3 chain; guanine nucleotide binding protein (G protein), beta polypeptide 3; guanine nucleotide binding protein (G protein), beta polypeptide 4; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding protein subunit beta-4; hypertension associated protein; Transducin beta chain 3; Transducin beta chain 4
基因别名: CMTD1F; CSNB1H; GNB3; GNB4
UniProt ID: (Human) P16520, (Human) Q9HAV0
Entrez Gene ID: (Human) 2784, (Human) 59345
