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Immunogen sequence: DVLVEYQGEG RNVTDPTCPS LSPGVSQCFP DCVCEDAYNN TYACVRTMSA LWNLQYCEFD DQEVFVEVYN LTADPDQITN IAKTIDPELL GKMNYRLMML QSCSGPTCRT PGVFDPGYRF DPRLMFSNRG SVRTRRF
GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: G6S; glucosamine -6-sulfatase; Glucosamine-6-sulfatase; N-acetylglucosamine-6-sulfatase
基因别名: G6S; GNS
UniProt ID: (Human) P15586
Entrez Gene ID: (Human) 2799
分子生物学功能: hydrolase