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Invitrogen
GOT1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-120951
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.438 mg/mL
规格
43.8 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: HepG2, U-251MG, Mouse brain, Mouse liver, Mouse heart, Rat brain, Rat liver, Rat kidney. The target is usually found in the following locations: Cytoplasm.
Immunogen sequence: FVSEGFEFFC AQSFSKNFGL YNERVGNLTV VGKEPESILQ VLSQMEKIVR ITWSNPPAQG ARIVASTLSN PELFEEWTGN VKTMADRILT MRSELRARLE ALKTPGTWNH ITDQIGMFSF TGLNPKQVEY LVNEKHIYLL PSGRINVSGL TTKNLDYVAT SIHEAVTKIQ
靶标信息
GOT1 is a glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aspartate aminotransferase; aspartate aminotransferase (EC 2.6.1.1); aspartate aminotransferase 1; aspartate transaminase 1; cysteine aminotransferase, cytoplasmic; cysteine transaminase, cytoplasmic; cytosolic aspartate aminotransferase; glutamate oxaloacetate transaminase 1; glutamate oxaloacetate transaminase 1, soluble; glutamic-oxaloacetic transaminase 1, soluble; growth-inhibiting protein 18; testis secretory sperm-binding protein Li 196a; transaminase A; unnamed protein product
基因别名: AAT1; ASAT; Aspat; AST; AST1; ASTQTL1; cAspAT; cCAT; Gaspat; GIG18; Got-1; SGOT
UniProt ID: (Human) P17174, (Mouse) P05201, (Rat) P13221
Entrez Gene ID: (Human) 2805, (Mouse) 14718, (Rat) 24401
catalytic activity
L-aspartate:2-oxoglutarate aminotransferase activity
phosphatidylserine decarboxylase activity
protein binding
transaminase activity
pyridoxal phosphate binding
carboxylic acid binding
L-cysteine:2-oxoglutarate aminotransferase activity
(2S)-2-aminobutanoate:2-oxoglutarate transaminase activity
gluconeogenesis
2-oxoglutarate metabolic process
oxaloacetate metabolic process
glycerol biosynthetic process
cellular amino acid metabolic process
aspartate metabolic process
aspartate biosynthetic process
aspartate catabolic process
glutamate metabolic process
response to carbohydrate
positive regulation of transforming growth factor beta receptor signaling pathway
cellular response to insulin stimulus
negative regulation of collagen biosynthetic process
response to immobilization stress
malate-aspartate shuttle
dicarboxylic acid metabolic process
response to cadmium ion
response to glucocorticoid
negative regulation of cytosolic calcium ion concentration
negative regulation of mitochondrial depolarization
transdifferentiation
cellular response to mechanical stimulus
cellular response to cAMP
cellular response to glucagon stimulus
L-glutamate biosynthetic process
response to transition metal nanoparticle
glutamate catabolic process
Notch signaling pathway
fatty acid homeostasis
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