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Invitrogen
GPN1 Polyclonal Antibody
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GPN1 Antibody (PA5-88392) in WB
Western blot analysis of GPN1 in extracts of various cell lines. Samples were incubated with GPN1 Polyclonal antibody (Product # PA5-88392) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88392
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 255-374 of human GPN1 (NP_009197.2).
偶联物
形式
Liquid
浓度
0.45 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse liver, Mouse lung, Mouse spleen; Cellular Location: Cytoplasm, Nucleus
Immunogen sequence: VGVSAVLGTG LDELFVQVTS AAEEYEREYR PEYERLKKSL ANAESQQQRE QLERLRKDMG SVALDAGTAK DSLSPVLHPS DLILTRGTLD EEDEEADSDT DDIDHRVTEE SHEEPAFQNF
靶标信息
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP(GTP)-binding protein; GPN-loop GTPase 1; MBD2-interacting protein; MBDin; methyl-CpG binding domain protein 2 interacting protein; RNA polymerase II associated protein 4; RNAPII-associated protein 4; XPA binding protein 1; XPA binding protein 1, GTPase; XPA-binding protein 1
基因别名: 2410004J02Rik; AI449615; ATPBD1A; GPN1; HUSSY-23; MBDIN; NTPBP; RPAP4; XAB1
UniProt ID: (Human) Q9HCN4, (Mouse) Q8VCE2
Entrez Gene ID: (Human) 11321, (Mouse) 74254
