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Invitrogen
GPR160 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-26509
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 305-332 amino acids from the C-terminal region of human GPR160
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
200 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
GPR160, part of the Class A family of G protein-coupled receptors (GPCRs), is prominently expressed in mouse embryonic stem cells and has been associated with various human solid tumors, particularly prostate cancer. The gene's expression contributes to the self-renewal and pluripotency of stem cells by participating in critical signaling pathways, including the JAK/STAT pathway, which is crucial for maintaining the stem cell cycle. High levels of GPR160 expression are observed in prostate cancer, though its role in disease progression is independent of the CARTp-mediated signaling pathway. Investigations into GPR160 have revealed its potential as a biomarker for prostate cancer. Additionally, it regulates mycobacteria entry into macrophages, implicating its functionality in immune responses. The gene's mechanisms of action, especially within cancer contexts, are subjects of ongoing research aimed at understanding its precise contributions to cellular proliferation and disease phenotypes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Probable G-protein coupled receptor 160
Gene Aliases: 1700025D19Rik; GPCR150; Gpr160
UniProt ID: (Mouse) Q3U3F9
Entrez Gene ID: (Mouse) 71862
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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