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Reconstitution: 1 X 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
GPR83, a 423 A.A protein, is an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR83 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: G protein-coupled receptor 72; G-protein coupled receptor 72; G-protein coupled receptor 83; glucocorticoid induced receptor; Glucocorticoid-induced receptor; Hcepto9; Jp05; probable G-protein coupled receptor 83
基因别名: AW045253; GIR; GPR72; GPR83; JP05; KIAA1540; RP105; RP39; RP82
UniProt ID: (Human) Q9NYM4, (Mouse) P30731, (Rat) Q8VHD7
Entrez Gene ID: (Human) 10888, (Mouse) 14608, (Rat) 140595
分子生物学功能: G-protein coupled receptor