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Invitrogen
GPSM2 Polyclonal Antibody
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Product Details
PA5-43683
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human GPSM2 (aa 72-121).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: YFYLHDYAKA LEYHHHDLTL ARTIGDQLGE AKASGNLGNT LKVLGNFDEA
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Target Information
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein signalling modulator 2 (AGS3-like, C. elegans); G-protein-signaling modulator 2; GPSM2; HGNC:29501; LGN protein; Mosaic protein LGN; unnamed protein product
Gene Aliases: CMCS; DFNB82; GPSM2; LGN; PINS
UniProt ID: (Human) P81274
Entrez Gene ID: (Human) 29899
establishment of mitotic spindle orientation
mitotic spindle organization
G-protein coupled receptor signaling pathway
response to light intensity
cell division
maintenance of centrosome location
regulation of mitotic spindle organization
neurotransmitter receptor localization to postsynaptic specialization membrane
positive regulation of protein localization to cell cortex
positive regulation of spindle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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