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Invitrogen
GPSM2 Polyclonal Antibody
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GPSM2 Antibody (PA5-87981) in WB
Western blot analysis of GPSM2 in extracts of various cell lines. Samples were incubated with GPSM2 Polyclonal antibody (Product # PA5-87981) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-87981
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 380-490 of human GPSM2 (NP_0374283)
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: STNNSIMSEN TEIDSSLNGV RPKLGRRHSM ENMELMKLTP EKVQNWNSEI LAKQKPLIAK PSAKLLFVNR LKGKKYKTNS STKVLQDASN SIDHRIPNSQ RKISADTIGD E; Positive Samples: B cells, HeLa, Mouse brain, Mouse liver, Mouse kidney; Cellular Location: Cytoplasm, cell cortex
靶标信息
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G-protein signalling modulator 2 (AGS3-like, C. elegans); G-protein-signaling modulator 2; HGNC:29501; LGN protein; Mosaic protein LGN; Pins homolog; pins homolog (Drosophia)
基因别名: 6230410J09Rik; CMCS; DFNB82; GPSM2; LGN; PINS
UniProt ID: (Human) P81274, (Mouse) Q8VDU0
Entrez Gene ID: (Human) 29899, (Mouse) 76123
