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Immunogen sequence: TLVQKCEVNG QNEHPVFAYL KDKLPYPYDD PFSLMTDPKL IIWSPVRRSD VAWNFEKFLI GPEGEPFRRY SRTFPTINIE P; Positive Samples: HepG2, HT-29, Mouse stomach, Rat small intestine
This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Gastrointestinal glutathione peroxidase; Glutathione peroxidase 2; glutathione peroxidase 2 (gastrointestinal); Glutathione peroxidase-gastrointestinal; Glutathione peroxidase-related protein 2; GPRP-2; GPx-2; GPx-GI; HGNC:4554; intestinal GPx; Phospholipid hydroperoxide glutathione peroxidase GPX2
基因别名: GI-GPx; GPRP; GPRP-2; GPx-2; GPX-GI; GPX2; GSHPx-2; GSHPX-GI
UniProt ID: (Human) P18283, (Mouse) Q9JHC0
Entrez Gene ID: (Human) 2877, (Mouse) 14776, (Rat) 29326
分子生物学功能: peroxidase