Invitrogen

GRAMD1A Monoclonal Antibody (1-E4)

Name: GRAMD1A Monoclonal Antibody (1-E4)
Brand: Invitrogen
SKU: MA5-32884
Price: 5026.00 CNY
Availability: InStock

查看其他7个GRAMD1A抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (9)

GRAMD1A Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 9

GRAMD1A Antibody (MA5-32884) in ICC/IF

Immunocytochemical analysis of GRAMD1A in HepG2 cells using a GRAMD1A Monoclonal antibody (Product # MA5-32884) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

GRAMD1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image GRAMD1A Monoclonal Antibody (1-E4)

产品信息

MA5-32884

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:400

免疫细胞化学 (ICC/IF)

1:50-1:200

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgM

分类

Monoclonal

类型

Antibody

克隆号

1-E4

抗原

Recombinant protein within Human GRAMD1A aa 1-724.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

200 µg

纯化类型

Protein A

保存液

PBS, pH 7.4, with 40% Glycerol, 0.2% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2802519

靶标信息

Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER. Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol. In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain. At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER. May play a role in tumor progression. Plays a role in autophagy regulation and is required for biogenesis of the autophagosome (PubMed:31222192). This function in autophagy requires its cholesterol-transfer activity (PubMed:31222192). [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。