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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • GluR1 Antibodies

          Abnova

          GRIA1 Recombinant Rabbit Monoclonal Antibody

          View all (39) GluR1 antibodies

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          Cite GRIA1 Recombinant Rabbit Monoclonal Antibody

          • Antibody Testing Data (1)
          GRIA1 Antibody in Western Blot (WB)
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          GRIA1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          GRIA1 Antibody (RAB01609) in WB

          Western blot analysis of Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) in C6 lysates using human Phospho-Glutamate Receptor 1 (AMPA subtype) (Ser845) recombinant monoclonal antibody, clone R03-7G4 (Product # RAB01609). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GRIA1 Antibody in Western Blot (WB)
          GRIA1 Recombinant Rabbit Monoclonal Antibody

          Product Details

          RAB01609

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          CHO cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to residues surrounding Ser845 of human AMPA Receptor 1 (GluA1).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Purification

          Affinity chromatography

          Storage buffer

          50mM tris glycine, pH 7.4, with 40% glycerol, 0.05% BSA, 150mM NaCl

          Contains

          0.01% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3710178

          Target Information

          GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: AI853806; AMPA 1; AMPA-selective glutamate receptor 1; GLUH 1; GluR K1; GluR-1; GluR-A; GluR-K1; GluRK1; glutamate receptor; Glutamate receptor 1; Glutamate receptor ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA 1; GPRC1A; Gria 1; GRM1A; HGBR1; HIPA; MGC13325; MGC133252; NMDA1; NMDAR1; NR1; OTTHUMP00000160643; OTTHUMP00000165781; OTTHUMP00000224241; OTTHUMP00000224242; OTTHUMP00000224243; RP11-350O14.1

          View more View less

          Gene Aliases: GLUA1; GLUH1; GLUR1; GLURA; GRIA1; HBGR1

          View more View less

          UniProt ID: (Human) P42261

          View more View less

          Entrez Gene ID: (Human) 2890

          View more View less

          Function(s)
          AMPA glutamate receptor activity excitatory extracellular ligand-gated ion channel activity extracellular-glutamate-gated ion channel activity protein binding glutamate receptor activity PDZ domain binding transmembrane signal receptor
          Process(es)
          ER to Golgi vesicle-mediated transport signal transduction chemical synaptic transmission long-term memory receptor internalization ion transmembrane transport ionotropic glutamate receptor signaling pathway COPII vesicle coating long term synaptic depression
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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