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Invitrogen
GRPEL2 Polyclonal Antibody
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产品信息
PA5-53747
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EPEDQKLTLE KVFRGLLLLE AKLKSVFAKH GLEKLTPIGD KYDPHEHELI CHVPAGVGVQ PGTVALVRQD GYKLHGRTIR LARVEVAVES
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.
靶标信息
GRPEL2 (GrpE Like 2, Mitochondrial) is a Protein Coding gene. Among its related pathways are Mitochondrial protein import and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding. An important paralog of this gene is GRPEL1. Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GrpE protein homolog 2, mitochondrial; GrpE-like 2, mitochondrial; Mt-GrpE#2
基因别名: GRPEL2; Mt-GrpE#2
UniProt ID: (Human) Q8TAA5
Entrez Gene ID: (Human) 134266
