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Invitrogen
GSDMB (Cleaved) Recombinant Rabbit Monoclonal Antibody (6F4K3)
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GSDMB (Cleaved) Antibody (MA5-55412) in WB
Western blot analysis of lysates from 293T GSDMB stable cells and 293T GSDMB stable cells transfected with GZMA using GSDMB (Cleaved) Recombinant Monoclonal Antibody (Product # MA5-55412) at 1:1,000 dilution followed by a HRP-conjugated Goat anti-Rabbit IgG (H+L) secondary antibody at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
MA5-55412
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6F4K3
抗原
A synthetic peptide corresponding to residues surrounding Ser245 of human Gasdermin B.
偶联物
形式
Liquid
浓度
1.11 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
RRID
产品详细信息
Immunogen Sequence: GKSLG
靶标信息
GSDMB (Cleaved) refers to the gene target Gasdermin B, which undergoes cleavage to produce active fragments. Gasdermin B is a protein that plays a role in the regulation of cell death and inflammation. Cleavage of GSDMB leads to the release of its N-terminal fragment, which can initiate a process called pyroptosis, a type of programmed cell death. Pyroptosis is an inflammatory form of cell death that is triggered by various stimuli, including infection and cellular stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Gasdermin B; Gasdermin-B; Gasdermin-like protein
基因别名: GSDMB; GSDML; PP4052; PRO2521
UniProt ID: (Human) Q8TAX9
Entrez Gene ID: (Human) 55876
