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Invitrogen
GSDMC Recombinant Rabbit Monoclonal Antibody (1G8H5)
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GSDMC Antibody (MA5-51281) in WB
Western blot analysis of GSDMC in extracts of various cell lines. Samples were incubated with GSDMC Recombinant monoclonal antibody (Product # MA5-51281) using a dilution of 1:10,000 followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
MA5-51281
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1G8H5
抗原
Recombinant protein (or fragment)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MPSMLERISK NLVKEIGSKD LTPVKYLLSA TKLRQFVILR KKKDSRSSFW EQSDYVPVEF SLNDILEPSS SVLETVVTGP FHFSDIMIQK HKADMGVNVG IEVSVSGEAS VDHGCSLEFQ IVTIPSPNLE DFQKRKLLDP EPSFLKECRR
靶标信息
The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: gasdermin C1; Gasdermin-C; Gasdermin-C1; melanoma-derived leucine zipper, extra-nuclear factor; Melanoma-derived leucine zipper-containing extranuclear factor; melanoma-derived leucine zipper-containing extranuclear factor {ECO:0000250|UniProtKB:Q9BYG8}; mMLZE
基因别名: GSDMC; Gsdmc1; MLZE
UniProt ID: (Human) Q9BYG8, (Mouse) Q99NB5
Entrez Gene ID: (Human) 56169, (Mouse) 83492, (Rat) 299908
