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Abnova
GTF2I Polyclonal Antibody, MaxPab™
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产品信息
H00002969-B01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GTF2I (AAH99907.1, 1 a.a. approximately 976 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK EESEDPDYYQ YNIQGPSETD DVDEKQPLSK PLQGSHHSSE GNEGTEMEVP AEDDDYSPPS KRPKANELPQ PPVPEPANAG KRKVREFNFE KWNARITDLR KQVEELFERK YAQAIKAKGP VTIPYPLFQS HVEDLYVEGL PEGIPFRRPS TYGIPRLERI LLAKERIRFV IKKHELLNST REDLQLDKPA SGVKEEWYAR ITKLRKMVDQ LFCKKFAEAL GSTEAKAVPY QKFEAHPNDL YVEGLPENIP FRSPSWYGIP RLEKIIQVGN RIKFVIKRPE LLTHSTTEVT QPRTNTPVKE DWNVRITKLR KQVEEIFNLK FAQALGLTEA VKVPYPVFES NPEFLYVEGL PEGIPFRSPT WFGIPRLERI VRGSNKIKFV VKKPELVISY LPPGMASKIN TKALQSPKRP RSPGSNSKVP EIEVTVEGPN NNNPQTSAVR TPTQTNGSNV PFKPRGREFS FEAWNAKITD LKQKVENLFN EKCGEALGLK QAVKVPFALF ESFPEDFYVE GLPEGVPFRR PSTFGIPRLE KILRNKAKIK FIIKKPEMFE TAIKESTSSK SPPRKINSSP NVNTTASGVE DLNIIQVTIP DDDNERLSKV EKARQLREQV NDLFSRKFGE AIGMGFPVKV PYRKITINRG CVVVDGMPPG VSFKAPSYLE ISSMRRILDS AEFIKFTVIR PFPGLVVNNQ LVDQSESEGP VIQESAEPSQ LEVPATEEIK ETDGSSQIKQ EPDPTW
靶标信息
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11. 23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BAP-135; Bruton tyrosine kinase-associated protein 135; BTK-associated protein 135; BTK-associated protein, 135kD; General transcription factor II-I; GTFII-I; OTTHUMP00000209509; SPIN; SRF-Phox1-interacting protein; tfiii; Williams-Beuren syndrome chromosomal region 6 protein; Williams-Beuren syndrome chromosome region 6
基因别名: 6030441I21Rik; BAP-135; BAP135; BTKAP1; DIWS; Diws1t; GTF2I; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6
UniProt ID: (Human) P78347, (Mouse) Q9ESZ8
Entrez Gene ID: (Human) 2969, (Mouse) 14886
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
signal transduction
transition between slow and fast fiber
negative regulation of angiogenesis
negative regulation of cytosolic calcium ion concentration
transcription, DNA-templated
regulation of transcription, DNA-templated
embryo development
