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Invitrogen
Galectin 1 Polyclonal Antibody, PeproTech®
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Galectin 1 Antibody (500-P210-1MG) in WB
Western Blot: To detect Human Galectin-1 by Western Blot analysis Galectin 1 Polyclonal Antibody (Product # 500-P210-1MG) can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human Galectin-1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
产品信息
500-P210-1MG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Chicken,
Hamster,
Human,
Mouse
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived Recombinant Human Galectin-1
偶联物
形式
Lyophilized
浓度
0.1-1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
产品详细信息
AA Sequence of recombinant protein: ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Galectin-1. Anti-Human Galectin-1-specific antibody was purified by affinity chromatography employing an immobilized Human Galectin-1 matrix.
Sandwich ELISA: To detect Human Galectin-1 by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human Galectin-1 (500-P210Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human Galectin-1.
Western Blot: To detect Human Galectin-1 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human Galectin-1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
靶标信息
Galectin-1 belongs to a large family of carbohydrate-binding proteins called lectins. Galectin-1can be either monomeric or homodimeric and is found in a wide variety of cells and tissue types. Galectin-1 can control cell growth, proliferation, induce apoptosis of activated T cells while it can also modulate cytokine secretion or inhibit pro-inflammatory cytokine production. Galectin-1 plays an important role in acute and chronic inflammation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 14 kDa laminin-binding protein; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14kDa; DKFZp686E23103; Gal-1; Galaptin; Galectin-1; Galectin1; H-Galectin-1; HBL; HLBP14; HPL; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; lectin, galactoside binding soluble 1; lectin, galactoside-binding, soluble, 1; pm12; Putative MAPK-activating protein PM12; S-Lac lectin 1
基因别名: GAL1; GBP; LGALS1
UniProt ID: (Human) B2R5E8
Entrez Gene ID: (Human) 3956
plasma cell differentiation
apoptotic process
signal transduction
negative regulation of cell-substrate adhesion
negative regulation of neuron projection development
T cell costimulation
multicellular organismal response to stress
positive regulation of erythrocyte aggregation
response to drug
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
myoblast differentiation
positive regulation of viral entry into host cell
response to axon injury
cellular response to glucose stimulus
cellular response to organic cyclic compound
positive regulation of dendritic cell differentiation
