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Invitrogen
Galectin 14 Polyclonal Antibody
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产品信息
PA5-139873
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: QFRLHFGHPA IMNSRVFGIW RYEEKCYYLP FEDGKPF
Highest antigen sequence indentity to the following orthologs: Rat - 32%, Mouse - 32%.
靶标信息
Galectin-14 is a member of the galectin family of proteins, which are characterized by their affinity for beta-galactoside sugars and involvement in various biological processes including cell-cell adhesion, immune response modulation, and apoptosis. The gene encoding Galectin-14, LGALS14, is located on chromosome 19q13.2. Galectin-14 is predominantly expressed in eosinophils and has been identified to play a role in allergic response and inflammation. It is known to participate in the modulation of immune responses, particularly asthma and other allergic conditions, by interacting with glycoproteins on cell surfaces. The expression of Galectin-14 is elevated during allergic reactions and this molecule is considered a potential biomarker for eosinophilic activity in such conditions. There is ongoing research into the exact mechanisms of Galectin-14 in immune response modulation, which might provide insights into novel therapeutic approaches for managing allergic diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charcot-Leyden crystal protein 2; CLC2; Gal-14; Galectin-14; lectin, galactoside binding soluble 14; lectin, galactoside-binding, soluble, 14; MGC22235; Placental protein 13-like; placental protein 13-like protein
基因别名: CLC2; LGALS14; PPL13
UniProt ID: (Human) Q8TCE9
Entrez Gene ID: (Human) 56891
