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Invitrogen
Galectin 3 Monoclonal Antibody (GT1188)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-50300
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
GT1188
抗原
Recombinant protein encompassing a sequence within the C-terminus region of human Galectin 3. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product can be used in Sandwich ELISA to detect Galectin 3 using MA5-50300 as a capture antibody and PA5-34912 as the detection antibody.
靶标信息
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 35 kDa lectin; advanced glycation end-product receptor 3; carbohydrate-binding protein 35; CBP-30; epididymis secretory sperm binding protein; epithelial-specific lectin; galactose-specific lectin 3; Galectin3; IgE-binding protein; L-29; laminin-binding protein; lectin L-29; lectin, galactoside-binding, soluble, 3; LGALS3; MAC-2 antigen; unnamed protein product
基因别名: CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
UniProt ID: (Human) P17931
Entrez Gene ID: (Human) 3958
monocyte chemotaxis
neutrophil chemotaxis
epithelial cell differentiation
positive regulation of protein complex assembly
killing of cells of other organism
regulation of T cell proliferation
negative regulation of endocytosis
eosinophil chemotaxis
macrophage chemotaxis
negative regulation of T cell receptor signaling pathway
positive chemotaxis
negative regulation of NK T cell activation
antimicrobial humoral immune response mediated by antimicrobial peptide
regulation of T cell apoptotic process
mononuclear cell migration
positive regulation of mononuclear cell migration
positive regulation of calcium ion import
regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of protein localization to plasma membrane
negative regulation of immunological synapse formation
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
positive regulation of dendritic cell differentiation
negative regulation of extrinsic apoptotic signaling pathway
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