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Galectin-6 is a member of the galectin family, characterized by its ability to bind specifically to beta-galactoside sugars. This protein is prominently expressed within the epithelial cells of the gastrointestinal tract in both embryonic and adult stages, appearing consistently from the stomach to the colon. Galectin-6 plays a significant role in the body's immune and microbial defense, acting as a novel anti-microbial peptide in the skin. It is known to be modulated by both the skin barrier and microbiome, emphasizing its involvement in maintaining skin homeostasis and protective functions. Beyond its antimicrobial roles, the galectin family, including galectin-6, is vital in regulating various cellular processes such as proliferation, adhesion, and migration, owing to its capacity to interact with specific glycans. This highlights galectin-6's broader implications in immune responses and inflammatory conditions, marking it as a potential focal point in studies relating to immunity and infection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Gal-6; Galectin-6
基因别名: galectin-6; Lgals6
UniProt ID: (Mouse) O54891
Entrez Gene ID: (Mouse) 16857