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Invitrogen
Ganglioside GD3 (Mitumomab Biosimilar) Recombinant Mouse Monoclonal Antibody
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Ganglioside GD3 (Mitumomab Biosimilar) Antibody (MA5-41752) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human Ganglioside GD4 protein expressed in CHO cells using a Ganglioside GD3 (Mitumomab Biosimilar) monoclonal antibody (Product # MA5-41752). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-41752
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human Ganglioside GD3.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.94 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Ganglioside GD3 is a glycosphingolipid (ceramide and oligosaccharide) or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. It is a component of the cell plasma membrane which modulates cell signal transduction events. Gangliosides have been found to be highly important in immunology. Ganglioside GD3 carries a net-negative charge at pH 7. 0 and is acidic. Gangliosides can amount to 6% of the weight of lipids from brain, but they are found at low levels in all animal tissues. Deficiencies in lysosomal enzymes that degrade the carbohydrate portions of various gangliosides are responsible for a number of lysosomal storage diseases such as Tay-Sachs disease, Sandhoff disease, and GM1 gangliosidosis. The carbohydrate portion of the ganglioside GM1 is the site of attachment of cholera toxin, the protein secreted by Vibrio cholerae.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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