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Invitrogen
Gram Negative Endotoxin Monoclonal Antibody (GNE13-305.6)
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产品信息
MA1-10685
产品规格
种属反应
Bacteria
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
GNE13-305.6
抗原
E. coli serotypes: O:111, B4 J5.
偶联物
形式
Liquid
浓度
1.8 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.2-7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-10685 detects Endotoxin from E. coli, Sh. sonnei, and S. typhimurium samples.
MA1-10685 has been successfully used in ELISA applications.
The MA1-10685 immunogen is E. coli serotypes: O:111, B4 J5.
靶标信息
Endotoxins are part of the outer membrane of the cell wall of gram-negative bacteria. Endotoxins are invariably associated with gram-negative bacteria whether the organisms are pathogens or not. Although the term "endotoxin" is occasionally used to refer to any cell-associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxin is associated with the lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram-negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram-negative bacterial infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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