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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Growth Hormone Antibodies

          NeoBiotechnologies

          Growth Hormone Recombinant Rabbit Monoclonal Antibody (GH, 4886R)

          查看其他45个Growth Hormone抗体

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          说明书
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          说明书
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          Cite Growth Hormone Recombinant Rabbit Monoclonal Antibody (GH, 4886R)

          • 抗体检测数据 (3)
          Growth Hormone Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          Growth Hormone Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          图: 1 / 3

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          Growth Hormone Antibody (2688-RBM6-P1ABX) in IHC (P)

          Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human brain using Growth Hormone Recombinant Monoclonal Antibody (Product # 2688-RBM6-P1ABX) at 2 µg/mL in PBS for 30 min RT. HIER: Tris/EDTA, pH9.0, 45 min. Secondary: HRP-polymer, 30 min. DAB, 5 min. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
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          查看产品

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          Growth Hormone Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Growth Hormone Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Growth Hormone Antibody in SDS-PAGE (SDS-PAGE)
          Growth Hormone Recombinant Rabbit Monoclonal Antibody (GH, 4886R)

          产品信息

          2688-RBM6-P1ABX

          应用
          建议稀释比
          已发表文章

          免疫组化(石蜡) (IHC (P))

          1-2 µg/mL
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Rabbit / IgG

          Expression System

          HEK293 cells

          分类

          Recombinant Monoclonal

          类型

          Antibody

          克隆号

          GH, 4886R

          抗原

          Recombinant full-length human GH1 protein
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Protein A/G

          保存液

          PBS, pH 7.4

          内含物

          no preservative

          保存条件

          -20°C or -80°C if preferred

          运输条件

          Ambient (domestic); Wet ice (international)

          产品详细信息

          Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

          靶标信息

          Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: GH; Growth hormone; Growth hormone 1; growth hormone B5; HGH; Pituitary growth hormone; rHGH; Somatotropin

          查看更多 收起

          基因别名: GH; GH-N; GH1; GHB5; GHN; hGH-N; IGHD1B

          查看更多 收起

          UniProt ID: (Human) P01241

          查看更多 收起

          Entrez Gene ID: (Human) 2688

          查看更多 收起

          功能
          growth hormone receptor binding prolactin receptor binding hormone activity protein binding growth factor activity metal ion binding peptide hormone
          参与通路
          positive regulation of receptor internalization JAK-STAT cascade positive regulation of activation of JAK2 kinase activity positive regulation of phosphatidylinositol 3-kinase signaling glucose transport response to estradiol positive regulation of multicellular organism growth positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein positive regulation of MAP kinase activity positive regulation of insulin-like growth factor receptor signaling pathway positive regulation of JAK-STAT cascade positive regulation of peptidyl-tyrosine phosphorylation growth hormone receptor signaling pathway JAK-STAT cascade involved in growth hormone signaling pathway bone maturation
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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