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Invitrogen
H-2Kb/H-2Db Monoclonal Antibody (5041.16.1), PE
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-18000
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
5041.16.1
抗原
Mouse H-2KbDb
偶联物
PE
PE
PE
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
浓度
0.1 mg/mL
规格
50 µg
纯化类型
Protein G
保存液
PBS with 4-5mg/mL BSA
内含物
0.02% sodium azide
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-18000 targets H-2KbDb in FACS applications and shows reactivity with Mouse samples.
The MA5-18000 immunogen is mouse H-2KbDb.
靶标信息
H-2KbDb monoclonal antibody is specific for cells expressing the H-2K antigen coded for by the b haplotype, and for cells expressing the H-2D antigen coded for by the b haplotype.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: class I major histocompatibility antigen H-2Kd; H-2 class I histocomatibility antigen, K-k alpha chain, topological domain; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2K(B); H-2K(K); H-2K(Q); H2-K; H2DB; H2KB; histocompatibility 2, K region, promoter 1; MHC class I alpha chain; MHC class I antigen; MHC class I H2 antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC class I heavy chain heavy chain; MHC class I heavy chain maturation peptide; MHC class II antigen D; MHC class II antigen K; MHC H-2K integral membrane protein; MHC H-2K transplantation antigen; MHC H-2K-kml mRNA; MHC H2-K antigen; MHC H2-K transplantation antigen; ORF; transmembrane protein; unnamed protein product
基因别名: H-2K; H-2K(d); H2-D1; H2-K; K-f
UniProt ID: (Mouse) P01901
Entrez Gene ID: (Mouse) 14972
receptor binding
protein binding
beta-2-microglobulin binding
MHC class I protein binding
peptide antigen binding
T cell receptor binding
CD8 receptor binding
identical protein binding
protein homodimerization activity
natural killer cell lectin-like receptor binding
TAP binding
TAP1 binding
TAP2 binding
receptor agonist activity
chaperone binding
TAP complex binding
14-3-3 protein binding
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
immune response
signal transduction
negative regulation of neuron projection development
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class I
defense response to bacterium
inner ear development
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