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Invitrogen
H2BK15ac Recombinant Rabbit Monoclonal Antibody (7H17L5)
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图: 1 / 5
H2BK15ac Antibody (701799) in ICC/IF
Immunofluorescence was performed on MCF7 cells treated with SAHA (0.5 uM/18 hours). These cells were permeabilized and fixed for detection of Histone H2BK15ac using Anti-Histone H2BK15ac Recombinant Rabbit Monoclonal Antibody (Product # 701799, 1 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 0.4 µg/mL, 1:2500). Panel a) shows representative cells that were stained for detection and localization of Histone H2BK15ac protein (green), Panel b) is stained... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
701799
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
7H17L5
抗原
Acetylated peptide (Lys15) corresponding to Human H2 (aa 11-18)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2-7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Since it is highly conserved across species, the antibody may react with many other species.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acetyl-Histone H2; Acetyl-Histone H2B K15; Acetyl-Histone H2B Lys15; H2B GL105; H2B histone family, member B; H2B histone family, member F; H2B-clustered histone 3; H2B-clustered histone 5; H2B/a; H2B/b; H2B/f; H2B/g; H2B/h; H2B/I; H2B/k; H2B/l; H2BK12ac; H2BK15ac; H2BK5ac; H2BLys15ac; H2BS14; H2BS14p; HIRA-interacting protein 2; HIST1H3I; histone 1, H2bb; histone 1, H2bd; Histone 2B; histone cluster 1 H2B family member b; histone cluster 1 H2B family member d; histone cluster 1, H2bb; histone cluster 1, H2bd; Histone H2B type 1-B; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-D; Histone H2B.1; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.a; Histone H2B.b; Histone H2B.f; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.k; Histone H2B.l; MGC125414; MGC125415; MGC125416; MGC9388; RP1-193B12.10; unnamed protein product
基因别名: dJ221C16.6; H2B.1; H2B.1B; H2B/a; H2B/b; H2B/f; H2B/g; H2B/h; H2B/k; H2B/l; H2BC10; H2BC3; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2BFA; H2BFB; H2BFF; H2BFG; H2BFH; H2BFK; H2BFL; HIRIP2; HIST1H2BB; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI
Entrez Gene ID: (Human) 3018, (Human) 3017
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
