Invitrogen

HBEGF Polyclonal Antibody

查看其他24个HBEGF抗体

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说明书
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说明书
实验方案
问题与答案
技术支持
HBEGF Polyclonal Antibody

产品信息

PA5-143862

应用
建议稀释比
已发表文章

免疫印迹 (WB)

0.25-0.5 µg/mL
-

免疫组化（石蜡） (IHC (P))

2-5 µg/mL
-

流式细胞分析 (Flow)

1-3 µg/1x10^6 cells
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence of human DTR/HBEGF (KKRDPCLRKYKDFCIHGECKYVKE).
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

500 µg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 4mg trehalose

内含物

no preservative

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_3075076

产品详细信息

Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

Positive Control - WB: human Hela whole cell, human K562 whole cell, human Jurkat whole cell, human U251 whole cell, rat C6 whole cell, mouse lung tissue. IHC: human lung adenocarcinoma tissue, human appendiceal adenocarcinoma tissue, mouse lung tissue, rat respiratory smooth muscle tissue. Flow: Jurkat cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

靶标信息

HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: diphtheria toxin receptor; Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor); diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); hb egf; heparin binding epidermal growth factor-like growth factor; heparin-binding EGF-like growth factor; heparin-binding epidermal -growth - like growth factor; heparin-binding epidermal -growth factor; heparin-binding epidermal growth factor; Proheparin-binding EGF-like growth factor

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基因别名: AW047313; DTR; DTS; DTSF; GFHB; Hb-egf; HBEGF; HEGFL

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UniProt ID: (Human) Q99075, (Mouse) Q06186, (Rat) Q06175

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Entrez Gene ID: (Human) 1839, (Mouse) 15200, (Rat) 25433

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