Abnova

HDAC9 Polyclonal Antibody, MaxPab™

Name: HDAC9 Polyclonal Antibody, MaxPab\u2122
Brand: Abnova
SKU: H00009734-B01P

查看其他21个HDAC9抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

图: 1 / 1

HDAC9 Antibody (H00009734-B01P) in WB

Western Blot analysis of HDAC9 expression in transfected 293T cell line by HDAC9 MaxPab polyclonal antibody. Lane 1: HDAC9 transfected lysate(117.59 KDa). Lane 2: Non-transfected lysate. .

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Immunogen image

Immunogen Image HDAC9 Polyclonal Antibody, MaxPab™

产品信息

H00009734-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫细胞化学 (ICC/IF)

10-100 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

HDAC9 (NP_848512.1, 1 a.a. approximately 1069 a.a) full-length human protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MHSMISSVDV KSEVPVGLEP ISPLDLRTDL RMMMPVVDPV VREKQLQQEL LLIQQQQQIQ KQLLIAEFQK QHENLTRQHQ AQLQEHIKLQ QELLAIKQQQ ELLEKEQKLE QQRQEQEVER HRREQQLPPL RGKDRGRERA VASTEVKQKL QEFLLSKSAT KDTPTNGKNH SVSRHPKLWY TAAHHTSLDQ SSPPLSGTSP SYKYTLPGAQ DAKDDFPLRK TASEPNLKVR SRLKQKVAER RSSPLLRRKD GNVVTSFKKR MFEVTESSVS SSSPGSGPSS PNNGPTGSVT ENETSVLPPT PHAEQMVSQQ RILIHEDSMN LLSLYTSPSL PNITLGLPAV PSQLNASNSL KEKQKCETQT LRQGVPLPGQ YGGSIPASSS HPHVTLEGKP PNSSHQALLQ HLLLKEQMRQ QKLLVAGGVP LHPQSPLATK ERISPGIRGT HKLPRHRPLN RTQSAPLPQS TLAQLVIQQQ HQQFLEKQKQ YQQQIHMNKL LSKSIEQLKQ PGSHLEEAEE ELQGDQAMQE DRAPSSGNST RSDSSACVDD TLGQVGAVKV KEEPVDSDED AQIQEMESGE QAAFMQQPFL EPTHTRALSV RQAPLAAVGM DGLEKHRLVS RTHSSPAASV LPHPAMDRPL QPGSATGIAY DPLMLKHQCV CGNSTTHPEH AGRIQSIWSR LQETGLLNKC ERIQGRKASL EEIQLVHSEH HSLLYGTNPL DGQKLDPRIL LGDDSQKFFS SLPCGGLGVD SDTIWNELHS SGAARMAVGC VIELASKVAS GELKNGFAVV RPPGHHAEES TAMGFCFFNS VAITAKYLRD QLNISKILIV DLDVHHGNGT QQAFYADPSI LYISLHRYDE GNFFPGSGAP NEVGTGLGEG YNINIAWTGG LDPPMGDVEY LEAFRTIVKP VAKEFDPDMV LVSAGFDALE GHTPPLGGYK VTAKCFGHLT KQLMTLADGR VVLALEGGHD LTAICDASEA CVNALLGNEL EPLAEDILHQ SPNMNAVISL QKIIEIQSKY WKSVRMVAVP RGCALAGAQL QEETETVSAL ASLTVDVEQP FAQEDSRTAG EPMEEEPAL

靶标信息

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is a critical component of transcriptional regulation and the acetylation of nucleosomal histones is a major source of this remodeling. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Several mammalian proteins function as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Conversely, the deacetylation of histones is associated with transcriptional silencing. The histone deacetylases (HDAC) include HDAC1-9. HDAC9 and HDAC9a are two alternatively spliced isoforms of HDAC9. HDAC9a is 132 amino acids shorter than HDAC9, but both isoforms contain the HDAC catalytic domain, remain capable of deacetylase activity and repress myoctye enhancer-binding factor 2-mediated transcription. HDAC9 and HDAC9a are expressed in brain, skeletal muscle, kidney, placenta and pancreas.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DKFZp779K1053; HD7; HD9; hdac-9; histone deacetylase 4/5-related protein; Histone deacetylase 7B; Histone deacetylase 9; Histone deacetylase-related protein; MEF-2 interacting transcription repressor (MITR) protein; MEF2-interacting transcription repressor MITR

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基因别名: HD7; HD7b; HD9; HDAC; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDRP; KIAA0744; MITR

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UniProt ID: (Human) Q9UKV0

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Entrez Gene ID: (Human) 9734

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功能