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Rockland
HDEL Monoclonal Antibody (2E7)
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产品信息
200-301-F44
产品规格
种属反应
Fruit fly,
Fungi,
Plant,
Yeast
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
2E7
抗原
HDEL Antibody was produced in mice by repeated immunizations raised against a synthetic HDEL synthetic peptide corresponding to the C-terminus of yeast Bip.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
HSP 70 family comprises four highly conserved proteins, HSP 70, HSC 70, GRP 75 and GRP 78, which serve a variety of roles. They act as molecular chaperones, facilitating the assembly of multi-protein complexes; participate in the translocation of polypeptides across cell membranes and to the nucleus; and aid in the proper folding of nascent polypeptide chains. GRP 78 is localized in the endoplasmic reticulum (ER), where it receives imported secretory proteins and is involved in the folding and translocation of nascent peptide chains. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually KDEL in animal cells, and HDEL in S.cerevisiae. The 2E7 clone recognizes the C-terminal peptide HDEL, a common version of the endoplasmic reticulum retention signal found in yeast, plant, nematode and other ER proteins. 2E7 specifically stains HDEL proteins in barnyard grass, beet, cotton, mung bean, sorghum and wheat.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CG5183-PA; CG5183-PB; CG5183-PC; ER lumen protein retaining receptor 2; ER lumen protein-retaining receptor; KDEL-receptor; KdelR-PA; KdelR-PB; KdelR-PC; KDELR1; lethal (2) 31Em
基因别名: BEST:CK00230; CG5183; CK00230; Dmel\CG5183; Dmel_CG5183; dmErd2; ERD2; KdelR; l(2)31Em; l(2)k00311
UniProt ID: (Fruit fly) O76767
Entrez Gene ID: (Fruit fly) 34427
