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Invitrogen
HEATR2 Polyclonal Antibody
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HEATR2 Antibody (PA5-100553) in ICC/IF
Immunocytochemistry analysis of HEATR2 in HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with HEATR2 polyclonal antibody (Product # PA5-100553) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-100553
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DNAAF5(Accession Q86Y56), corresponding to amino acid residues G313-A363.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total HEATR2.
靶标信息
The protein encoded by this gene is essential for the preassembly or stability of axonemal dynein arms, and is found only in organisms with motile cilia and flagella. Mutations in this gene are associated with primary ciliary dyskinesia-18, a disorder characterized by abnormalities of motile cilia. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dynein (axonemal) assembly factor 5; Dynein axonemal assembly factor 5; dynein, axonemal, assembly factor 5; HEAT repeat containing 2; HEAT repeat-containing protein 2
基因别名: CILD18; DNAAF5; HEATR2
UniProt ID: (Human) Q86Y56
Entrez Gene ID: (Human) 54919, (Rat) 304332
