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Invitrogen
HELT Polyclonal Antibody
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产品信息
PA5-48608
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 131-160 amino acids from the Central region of human HELT.
偶联物
形式
Liquid
浓度
0.45 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted to react with zebrafish based on sequence homology.
靶标信息
Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3'.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLH transcription factor megane; Hairy and enhancer of split-related protein HELT; HES/HEY-like transcription factor; Heslike; Hey-like transcription factor; Hey-like transcriptional repressor; Megane bHLH factor; mesencephalic GABAergic neurons enhancer of split related protein; Protein Hes-like; Protein megane
基因别名: A830086M02; bHLHb44; HCM1228; HELT; HESL; megane; Mgn
UniProt ID: (Human) A6NFD8, (Mouse) Q7TS99
Entrez Gene ID: (Human) 391723, (Mouse) 234219
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein homodimerization activity
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein dimerization activity
basic helix-loop-helix transcription factor
negative regulation of transcription from RNA polymerase II promoter
suckling behavior
transcription, DNA-templated
central nervous system development
post-embryonic development
multicellular organism aging
GABAergic neuron differentiation in basal ganglia
multicellular organism growth
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
nervous system development
gene expression
cell differentiation
neuron differentiation
