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Invitrogen
HEN1/HEN2 Monoclonal Antibody (2A3)
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产品信息
MA5-19463
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2A3
抗原
NHLH2 (NP_005590, 36 a.a. ~ 135 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide Sequence: SDLEPVEEAE GDGKGGSRAA LYPHPQQLSR EEKRRRRRAT AKYRSAHATR ERIRVEAFN LAFAELRKLL PTLPPDKKLS KIEILRLAIC YISYLNHVLD V
靶标信息
The helix-loop-helix (HLH) structures are known motifs commonly found in membrane-active and DNA-binding proteins. Helix-loop-helix proteins (HEN1 and HEN2) are DNA-binding proteins that may be involved in cell-type determination in the early nervous system. Studies of expression in normal tissues have demonstrated expression of NSCL-1 and NSCL-2 (genes encoding HEN1 and HEN2) in the developing central and peripheral nervous system, specifically in developing neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHa34; bHLHa35; Class A basic helix-loop-helix protein 34; Class A basic helix-loop-helix protein 35; Helix-loop-helix protein 1; Helix-loop-helix protein 2; HEN-1; HEN-2; Nescient helix loop helix 1; Nescient helix loop helix 2; NSCL-1; NSCL-2
基因别名: BHLHA34; BHLHA35; HEN1; HEN2; KIAA0490; NHLH1; NHLH2; NSCL; NSCL1; NSCL2
UniProt ID: (Human) Q02575, (Human) Q02577
Entrez Gene ID: (Human) 4807, (Human) 4808
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein dimerization activity
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
protein binding
basic helix-loop-helix transcription factor
transcription from RNA polymerase II promoter
central nervous system development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
mating behavior
ovulation cycle
positive regulation of sequence-specific DNA binding transcription factor activity
