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Abnova
HES5 Monoclonal Antibody (3C5)
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产品信息
H00388585-M01
产品规格
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
3C5
抗原
HES5 (NP_001010926, 28 a.a. approximately 121 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: RRDRINSSIE QLKLLLEQEF ARHQPNSKLE KADILEMAVS YLKHSKAFVA AAGPKSLHQD YSEGYSWCLQ EAVQFLTLHA ASDTQMKLLY HFQR
靶标信息
Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 is reported to be a down stream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma. Reports also suggest that HES5 is abundantly expressed in osteoarthritis along with Notch1 and Jagged1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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