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Invitrogen
HIST1H2AJ Polyclonal Antibody
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Product Details
PA5150289
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Histone Cluster 1, H2aj (HIST1H2AJ) (Met1-Lys128)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The HIST1H2AJ gene encodes a variant of the H2A family of histones, which are fundamental components of the nucleosome structure in eukaryotic cells. Histones are responsible for packaging DNA into chromatin and play a critical role in regulating gene expression. The modifications of these histones, including those produced by the HIST1H2AJ gene, can influence DNAtemplated processes such as transcription, replication, and repair by altering chromatin structure. The histone modifications are complex and include acetylation, methylation, and lactylation, which serve as a dynamic regulatory mechanism linking cellular metabolism to gene regulation. This connection illustrates the intricate role histone modifications have in responding to cellular stress and damage, thereby impacting processes such as inflammation and cancer development. The comprehensive understanding of histone posttranslational modifications and their effect on gene expression underscores the importance of HIST1H2AJ within the broader study of chromatin dynamics and its influence on human health and disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H2A histone family, member E; histone 1, H2aj; Histone H2A type 1-J; Histone H2A/e
Gene Aliases: dJ160A22.4; H2A/E; H2AC14; H2AFE; HIST1H2AJ
UniProt ID: (Human) Q99878
Entrez Gene ID: (Human) 8331
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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