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Invitrogen
HJURP Recombinant Rabbit Monoclonal Antibody (K01_2M72)
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HJURP Antibody (MA564086) in IHC (P)
Immunohistochemistry (Paraffin) analysis of HJURP in paraffin-embedded Human lung cancer tissue. Samples were incubated with HJURP recombinant monoclonal (Product # MA564086). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
产品信息
MA564086
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_2M72
抗原
Recombinant protein of human HJURP.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
50mM tris glycine, pH 7.4, with 40% glycerol, 150mM NaCl, 0.05% BSA
内含物
0.01% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. It acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. It directly binds to Holliday junctions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 14-3-3-associated AKT substrate; fetal liver expressing gene 1; Fetal liver-expressing gene 1 protein; Holliday junction recognition protein; Up-regulated in lung cancer 9
基因别名: FAKTS; FLEG1; hFLEG1; HJURP; URLC9
UniProt ID: (Human) Q8NCD3
Entrez Gene ID: (Human) 55355
