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Invitrogen
HK1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-87969
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.3 mg/mL
规格
130 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KIDKYLYAMR LSDETLIDIM TRFRKEMKNG LSRDFNPTAT VKMLPTFVRS IPDGSEKGDF IALDLGGSSF RILRVQVNHE KNQNVHMESE VYDTPENIVH GSGSQLFDHV AECLGDFMEK RKIKDKKLPV GFTFSFPCQQ SKIDEAILIT WTKRFKASGV EGADVVKLLN KAIKKRGDYD ANIVAVVNDT VGTMMTCGY
Positive Samples: MCF7, 293T, Jurkat, THP-1, NIH/3T3, K-562, Mouse skeletal muscle, rat testis; Cellular Location: Mitochondrion outer membrane
靶标信息
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP:D-hexose 6-phosphotransferase; brain form hexokinase; CNSHA5; downeast anemia; glycolytic enzyme; hexokinase; hexokinase (EC 2.7.1.1); hexokinase IR; hexokinase type I; hexokinase, tumor isozyme; hexokinase-A; HK; HK I; HK1-ta; HK1-tb; HK1-tc; HK1-td; HKD; HKI; HMSNR; HXK1; NEDVIBA; Neuropathy, hereditary motor and sensory, Russe type; NMSR; RP79; unnamed protein product
基因别名: CNSHA5; dea; HEXOKIN; hexokinase; HK; Hk-1; Hk1-s; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; mHk1-s; NEDVIBA; NMSR; RP79
UniProt ID: (Human) P19367, (Rat) P05708, (Mouse) P17710
Entrez Gene ID: (Human) 3098, (Rat) 25058, (Mouse) 15275
response to hypoxia
cellular glucose homeostasis
positive regulation of cytokine production involved in immune response
response to ischemia
carbohydrate metabolic process
fructose 6-phosphate metabolic process
glucose metabolic process
mannose metabolic process
glycolytic process
protein phosphorylation
GDP-mannose biosynthetic process
response to brassinosteroid
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
hexose metabolic process
positive regulation of interleukin-1 beta production
negative regulation of apoptotic process
protein autophosphorylation
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
protein localization to mitochondrion
maintenance of protein location in mitochondrion
response to ketamine
negative regulation of anion transmembrane transport
organophosphate metabolic process
carbohydrate derivative metabolic process
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