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Invitrogen
HLA-B7 Recombinant Mouse Monoclonal Antibody (BB7.1)
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HLA-B7 Antibody (MA5-56743) in Flow
Flow Cytometry analysis of HLA-B7 in non-fixed and non-permeabilized PBMC; gated on granulocytes using HLA-B7 Recombinant Monoclonal antibody (Product # MA5-56743). Black: Unlabelled sample was used as a control. Red: HLA-B7 antibody (MA5-56743) at a dilution of 1:50. Acquisition of 20,000 events were collected using a Alexa Flour 488-conjugated secondary antibody for FACS analysis.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-56743
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
BB7.1
抗原
The immunogen used to generate this antibody corresponds to human HLA-B7.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
HLA-B7 is one of the polymorphic proteins of human MHC Class I found on all nucleated cells. This surface protein is a heterodimer consisting of the specific transmembrane HLA-B chain paired with Beta-2 microglobulin. Classical MHC Class I molecules play a central role in adaptive immunity by presenting to T cells antigenic peptides derived either from the cell itself (classical presentation) or extracellular antigens (cross-presentation). The ligands of MHC class I include T cell receptor (TCR) and a costimulatory molecule CD8. Hundreds of HLA-B alleles have been described. Typing for these polymorphisms is routinely done for transplantation.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDABP0067; DAQB-90C11.16; FLJ26655; hla b7; HLA class I histocompatibility antigen, B alpha chain; HLA-B; HLA-B 1502; Human leukocyte antigen B; MHC 1; MHC1
基因别名: HLA-B; HLAB
Entrez Gene ID: (Human) 3106
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