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Invitrogen
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Purity is > 95% by SDS-PAGE.
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ10739; High mobility group protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1; iBRAF; Inhibitor of BRAF35
基因别名: 1200004E06Rik; 5730490E10Rik; HMG20A; HMGX1; HMGXB1; Ibraf
UniProt ID: (Human) Q9NP66, (Mouse) Q9DC33
Entrez Gene ID: (Human) 10363, (Mouse) 66867