Abnova

HMG20B Polyclonal Antibody, MaxPab™

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说明书
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说明书
实验方案
问题与答案
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说明书
实验方案
问题与答案
技术支持
HMG20B Polyclonal Antibody, MaxPab™

产品信息

H00010362-D01P

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:1,000
-
产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

HMG20B (NP_006330.2, 1 a.a. approximately 317 a.a) full-length human protein.
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: MSHGPKQPGA AAAPAGGKAP GQHGGFVVTV KQERGEGPRA GEKGSHEEEP VKKRGWPKGK KRKKILPNGP KAPVTGYVRF LNERREQIRT RHPDLPFPEI TKMLGAEWSK LQPTEKQRYL DEAEREKQQY MKELRAYQQS EAYKMCTEKI QEKKIKKEDS SSGLMNTLLN GHKGGDCDGF STFDVPIFTE EFLDQNKARE AELRRLRKMN VAFEEQNAVL QRHTQSMSSA RERLEQELAL EERRTLALQQ QLQAVRQALT ASFASLPVPG TGETPTLGTL DFYMARLHGA IERDPAQHEK LIVRIKEILA QVASEHL

靶标信息

Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 94 kDa B-raf protein; B-Raf proto-oncogene serine/threonine-protein kinase (p94); BRCA2-associated factor 35; FLJ26127; high mobility group 20 B; high mobility group protein 20 B; high-mobility group 20B; HMG box domain containing 2; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; murine sarcoma viral (v-raf) oncogene homolog B1; p94; Proto-oncogene B-Raf; Serine/threonine-protein kinase B-raf; SMARCE1-related protein; Sox-like transcriptional factor; Structural DNA-binding protein BRAF35; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1-related; v-raf murine sarcoma viral oncogene homolog B; v-Raf murine sarcoma viral oncogene homolog B1

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基因别名: 9930012E13Rik; AA120551; AA387315; AA473386; AW610687; B-raf; B-RAF1; BRAF; Braf-2; BRAF1; Braf2; BRAF25; BRAF35; C230098H17; C87398; D6Ertd631e; HMG20B; HMGX2; HMGXB2; NS7; PP7706; pp8857; RAFB1; SMARCE1R; SOXL

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UniProt ID: (Human) P15056, (Mouse) P28028, (Human) Q9P0W2, (Mouse) Q9Z104

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Entrez Gene ID: (Human) 673, (Mouse) 109880, (Human) 10362, (Mouse) 15353

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功能
protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding small GTPase binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity nucleotide binding receptor signaling protein activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups metal ion binding DNA binding histone deacetylase activity four-way junction DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding non-receptor serine/threonine protein kinase
参与通路
MAPK cascade activation of MAPKK activity myeloid progenitor cell differentiation protein phosphorylation visual learning organ morphogenesis positive regulation of gene expression negative regulation of fibroblast migration glucose transport thyroid gland development positive regulation of peptidyl-serine phosphorylation somatic stem cell population maintenance cellular response to drug regulation of cell proliferation negative regulation of apoptotic process CD4-positive, alpha-beta T cell differentiation positive T cell selection response to peptide hormone negative regulation of neuron apoptotic process thymus development positive regulation of axon regeneration positive regulation of axonogenesis protein heterooligomerization positive regulation of stress fiber assembly response to cAMP long-term synaptic potentiation head morphogenesis face development positive regulation of ERK1 and ERK2 cascade cellular response to calcium ion establishment of protein localization to membrane positive regulation of substrate adhesion-dependent cell spreading negative regulation of synaptic vesicle exocytosis negative regulation of endothelial cell apoptotic process signal transduction phosphorylation cell differentiation intracellular signal transduction alpha-beta T cell differentiation regulation of axon regeneration transcription, DNA-templated regulation of transcription, DNA-templated cell cycle blood coagulation histone deacetylation negative regulation of protein sumoylation skeletal muscle cell differentiation positive regulation of neuron differentiation chromatin organization chromatin remodeling chromatin modification
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