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Invitrogen
HMGCS2 Polyclonal Antibody
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图: 1 / 4
HMGCS2 Antibody (PA5-112573) in ICC/IF
Immunocytochemichal analysis of HMGCS2 in HepG2 cells using a Polyclonal antibody (Product # PA5-112573) at a dilution of 1:133. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L). Cells were also counter-stained with DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-112573
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Hydroxymethylglutaryl-CoA synthase, mitochondrial protein (426-508AA)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.79 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-hydroxy-3-methylglutary-Coenzyme A synthase 2; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial); HMG-CoA synthase; hydroxymethylglutaryl-CoA synthase 2; Hydroxymethylglutaryl-CoA synthase, mitochondrial
基因别名: Hmgcs1; HMGCS2; Mt3h3mg
UniProt ID: (Rat) P22791
Entrez Gene ID: (Rat) 24450
kidney development
liver development
cholesterol biosynthetic process
brain development
midgut development
response to nutrient
isoprenoid biosynthetic process
response to temperature stimulus
response to bacterium
response to metal ion
response to organic cyclic compound
lung development
response to insulin
cellular response to insulin stimulus
cellular response to hormone stimulus
multicellular organismal response to stress
response to testosterone
response to glucagon
response to triglyceride
response to monosaccharide
response to prostaglandin F
response to drug
response to starvation
response to peptide hormone
response to ethanol
ketone body biosynthetic process
response to glucocorticoid
response to cAMP
response to growth hormone
adipose tissue development
response to fatty acid
response to linoleic acid
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to glucocorticoid stimulus
cellular response to fatty acid
cellular response to organic cyclic compound
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