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Invitrogen
HMGCS2 Polyclonal Antibody
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HMGCS2 Antibody (PA5-85502) in IHC (P)
HMGCS2 Polyclonal Antibody detects HMGCS2 protein at mitochondria on human liver carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human liver carcinoma. HMGCS2 Polyclonal Antibody (Product # PA5-85502) diluted at 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-85502
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human HMGCS2. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (85%), Rat (85%), Bovine (83%).
Positive Control: human HMGCS2-transfected 293T cells.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial); HMG-CoA synthase; HMGCS2; testicular tissue protein Li 88; unnamed protein product
UniProt ID: (Human) P54868
Entrez Gene ID: (Human) 3158
kidney development
liver development
acetyl-CoA metabolic process
midgut development
response to nutrient
isoprenoid biosynthetic process
response to temperature stimulus
response to xenobiotic stimulus
response to bacterium
response to metal ion
farnesyl diphosphate biosynthetic process, mevalonate pathway
lung development
response to insulin
cellular response to insulin stimulus
cellular response to hormone stimulus
multicellular organismal response to stress
response to testosterone
response to glucagon
response to triglyceride
response to monosaccharide
response to prostaglandin F
response to starvation
response to peptide hormone
response to ethanol
ketone body biosynthetic process
response to glucocorticoid
response to cAMP
response to growth hormone
adipose tissue development
response to fatty acid
response to linoleic acid
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to glucocorticoid stimulus
cellular response to fatty acid
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