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Positive Samples: Mouse liver; Cellular Location: Nucleus
Immunogen sequence: RQCVVDKDKR NQCRYCRLKK CFRAGMKKEA VQNERDRIST RRSSYEDSSL PSINALLQAE VLSRQITSPV SGINGDIRAK KIASIADVCE SMKEQLLVLV E
Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ39654; Hepatocyte nuclear factor 4-alpha; HNF-4-alpha; HNF4 alpha; HNF4-alpha; HNF4alpha10; HNF4alpha11; HNF4alpha12; Nuclear receptor 2A1; Nuclear receptor subfamily 2 group A member 1; TCF-14; Transcription factor 14; Transcription factor HNF-4
基因别名: HNF-4; Hnf4; Hnf4a; Hnf4alpha; MODY1; Nr2a1; Tcf14
UniProt ID: (Mouse) P49698
Entrez Gene ID: (Mouse) 15378
分子生物学功能: C4 zinc finger nuclear receptor